Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylacetylene SCHEMBL8847150 | 0.86 | TSHR (0.70) | DAOTSHRNAPRTNPC1RAB9A | |
| SCHEMBL3792911 | 0.84 | APP (0.63) | TSHRNPC1RAB9AAPPFFAR1 | |
| SCHEMBL402518 | 0.80 | RARB (0.62) | DAOTSHRNAPRTSLC16A3CES2 | |
| SCHEMBL17014854 | 0.79 | SLC16A3 (0.54) | DAOTSHRNAPRTNPC1RAB9A | |
| SCHEMBL5052289 | 0.78 | APP (0.55) | NPC1RAB9AAPPHNF4AFFAR1 | |
| Hydrochloric Acid SCHEMBL2707922 | 0.78 | RARB (0.60) | DAOTSHRNAPRTSLC16A3CES2 | |
| SCHEMBL5141153 | 0.78 | APP (0.55) | NPC1RAB9AAPPHNF4AFFAR1 | |
| SCHEMBL5666516 | 0.76 | TTR (0.49) | DAOTSHRNAPRTNPC1RAB9A | |
| SCHEMBL22824251 | 0.76 | RARB (0.53) | DAOTSHRNAPRTSLC16A3CES2 | |
| SCHEMBL5004421 | 0.75 | NPC1 (0.53) | TSHRNPC1RAB9ASLC16A3APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109249-B2 | Composition containing a cross-linkable matrix precursor and a poragen, and porous matrix prepared therefrom | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-09-19 | — | — | US | disclosed |
| US-6887910-B2 | Composition containing a cross-linkable matrix precursor and a poragen, and a porous matrix prepared therefrom | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-05-03 | — | — | US | disclosed |
| US-20050014855-A1 | Composition containing a cross-linkable matrix precursor and a poragen, and a porous matrix prepared therefrom | BRUZA KENNETH J (US) | 2005-01-20 | — | — | US | disclosed |
| US-6653358-B2 | Electronics; integrated circuits; containing benzocyclobutene polymer | DOW GLOBAL TECHNOLOGIES INC. | 2003-11-25 | — | — | US | disclosed |
| US-6630520-B1 | Matrix precursor comprises a material selected from cyclopentadienone and acetylene functional compounds, at least some of which have three or more reactive functional groups; partially polymerized reaction products and perfluoroethylenes | DOW GLOBAL TECHNOLOGIES INC. | 2003-10-07 | — | — | US | disclosed |
| US-20030092785-A1 | Composition containing a cross-linkable matrix precursor and a poragen, and a porous matrix prepared therefrom | BRUZA KENNETH J (US) | 2003-05-15 | — | — | US | disclosed |
| US-20030083392-A1 | Composition containing a cross-linkable matrix precursor and a poragen, and a porous matrix prepared therefrom | BRUZA KENNETH J (US) | 2003-05-01 | — | — | US | disclosed |