Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 8/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.50 |
| ▸ | BRAF | P15056 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5770944 | 0.89 | MAPK13 (0.54) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL5771018 | 0.88 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL6074976 | 0.88 | MAPK13 (0.53) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL5771449 | 0.87 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL5772653 | 0.86 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL5773225 | 0.86 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL5771039 | 0.85 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL5769386 | 0.85 | MAPK14 (0.53) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5771026 | 0.85 | MAPK14 (0.56) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL5772499 | 0.85 | MAPK13 (0.58) | MAPK13MAPK12MAPK11MAPK14BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989395-B2 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2006-01-24 | — | — | US | disclosed |