SCHEMBL6075628

SCHEMBL6075628

CCCCCn1c(=O)c2ccc(c1=O)c1c3ccc(c(=O)n(CCCCC)c3=O)c21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
PGR P06401 2/20 0.50
RORA P35398 2/20 0.50
RORC P51449 2/20 0.50
RORB Q92753 2/20 0.50
ALDH1A1 P00352 4/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
KDM4E B2RXH2 2/20 0.48
GAA P10253 1/20 0.48
HTT P42858 1/20 0.46
TP53 P04637 1/20 0.44
HSP90AA1 P07900 1/20 0.44
CYP3A4 P08684 1/20 0.44
G6PD P11413 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
HIF1A Q16665 1/20 0.44
ADORA2B P29275 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL54244 0.98 TDP1 (0.59) TDP1L3MBTL1PGRRORARORC
SCHEMBL15057066 0.98 TDP1 (0.59) TDP1L3MBTL1PGRRORARORC
SCHEMBL6075749 0.98 TDP1 (0.59) TDP1L3MBTL1PGRRORARORC
SCHEMBL3111548 0.94 TDP1 (0.69) TDP1L3MBTL1PGRRORARORC
SCHEMBL19052076 0.88 TDP1 (0.50) TDP1L3MBTL1PGRRORARORC
SCHEMBL19052077 0.87 TDP1 (0.49) TDP1L3MBTL1PGRRORARORC
SCHEMBL19052083 0.87 TDP1 (0.49) TDP1L3MBTL1PGRRORARORC
SCHEMBL6076720 0.85 TDP1 (0.52) TDP1L3MBTL1PGRRORARORC
SCHEMBL15057621 0.83 TDP1 (0.45) TDP1L3MBTL1PGRRORARORC
SCHEMBL15057939 0.83 TDP1 (0.45) TDP1L3MBTL1PGRRORARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040151996-A1 Photoconductive members XEROX CORPORATION 2004-08-05 US claimed
US-7037630-B2 Photoconductive members XEROX CORPORATION (US) 2006-05-02 US disclosed
US-20040151996-A1 Photoconductive members XEROX CORPORATION 2004-08-05 US disclosed