Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 5/20 | 0.39 |
| ▸ | CES1 | P23141 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrous Acid SCHEMBL4825101 | 0.93 | KMT2A (0.43) | KMT2ADGKAALDH1A1CES2CES1 | |
| SCHEMBL34065 | 0.93 | — | — | |
| SCHEMBL10951377 | 0.90 | KMT2A (0.46) | KMT2ALPAR3LPAR1LPAR2NAAA | |
| SCHEMBL8442646 | 0.90 | KMT2A (0.46) | KMT2ALPAR3LPAR1LPAR2NAAA | |
| SCHEMBL11303507 | 0.90 | KMT2A (0.46) | KMT2ALPAR3LPAR1LPAR2NAAA | |
| SCHEMBL552425 | 0.90 | KMT2A (0.46) | KMT2ALPAR3LPAR1LPAR2NAAA | |
| SCHEMBL294422 | 0.90 | KMT2A (0.46) | KMT2ALPAR3LPAR1LPAR2NAAA | |
| SCHEMBL9220001 | 0.90 | KMT2A (0.46) | KMT2ALPAR3LPAR1LPAR2NAAA | |
| SCHEMBL9224792 | 0.90 | KMT2A (0.46) | KMT2ALPAR3LPAR1LPAR2NAAA | |
| SCHEMBL10331011 | 0.90 | KMT2A (0.46) | KMT2ALPAR3LPAR1LPAR2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323461-B2 | Use of methylene blue and related compounds to prevent or reverse an exaggerated hemodynamic reaction | MONTREAL HEART INSTITUTE (CA) | 2008-01-29 | — | — | US | claimed |
| US-8486621-B2 | Nucleic acid-based matrixes | CORNELL RESEARCH FOUNDATION, INC. (US) | 2013-07-16 | — | — | US | disclosed |
| US-20120045430-A1 | DENDRIMER-LIKE MODULAR DELIVERY VECTOR | CORNELL UNIVERSITY | 2012-02-23 | — | — | US | disclosed |
| US-20120040397-A1 | Photo-Crosslinked Nucleic Acid Hydrogels | CORNELL UNIVERSITY | 2012-02-16 | — | — | US | disclosed |
| EP-2324045-A2 | PHOTO-CROSSLINKED NUCLEIC ACID HYDROGELS | Cornell University (US) | 2011-05-25 | — | — | EP | disclosed |
| US-20100136614-A1 | Dendrimer-like modular delivery vector | LUO DAN | 2010-06-03 | — | — | US | disclosed |
| WO-2010017264-A2 | PHOTO-CROSSLINKED NUCLEIC ACID HYDROGELS | CORNELL UNIVERSITY (US) | 2010-02-11 | — | — | WO | disclosed |
| US-20080280955-A1 | Methods and compositions for screening and treatment of disorders of blood glucose regulation | PERLEGEN SCIENCES, INC. (US) | 2008-11-13 | — | — | US | disclosed |
| EP-1931805-A2 | METHODS AND COMPOSITIONS FOR SCREENING AND TREATMENT OF DISORDERS OF BLOOD GLUCOSE REGULATION | Perlegen Sciences, Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| US-20070148246-A1 | Nucleic Acid-Based Matrixes | CORNELL RESEARCH FOUNDATION INC. | 2007-06-28 | — | — | US | disclosed |
| US-20070117177-A1 | Nucleic Acid-Based Matrixes for Protein Production | CORNELL RESEARCH FOUNDATION, INC. | 2007-05-24 | — | — | US | disclosed |
| WO-2007038670-A2 | METHODS AND COMPOSITIONS FOR SCREENING AND TREATMENT OF DISORDERS OF BLOOD GLUCOSE REGULATION | PERLEGEN SCIENCES, INC. (US) | 2007-04-05 | — | — | WO | disclosed |