Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6079506 | 0.89 | KDM4E (0.53) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL6596077 | 0.86 | SMARCA2 (0.41) | KDM4ESMARCA2SMARCA4PBRM1CHEK1 | |
| Hydrochloric Acid SCHEMBL6080310 | 0.85 | SMARCA2 (0.40) | KDM4ESMARCA2SMARCA4PBRM1CHEK1 | |
| SCHEMBL6079337 | 0.78 | KDM4E (0.48) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6080185 | 0.77 | KDM4E (0.40) | KDM4EMEN1KMT2ANQO2ALDH1A1 | |
| SCHEMBL6080542 | 0.76 | NQO2 (0.46) | KDM4ENQO2ALDH1A1MAPTHPGD | |
| SCHEMBL6080136 | 0.76 | KDM4E (0.48) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6595426 | 0.75 | GAA (0.49) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL6080435 | 0.74 | GAA (0.48) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL6080466 | 0.71 | EGFR (0.46) | KDM4ESMN1; SMN2MEN1KMT2ANQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | KDM4E 1006/4885NPC1 1911/4885RAB9A 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.