Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722316 | 0.92 | MEN1 (0.53) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL5854578 | 0.87 | MEN1 (0.41) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL5353382 | 0.87 | MEN1 (0.41) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL5854564 | 0.85 | MEN1 (0.41) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL7516322 | 0.84 | MEN1 (0.59) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL11063113 | 0.84 | MEN1 (0.59) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL7516454 | 0.84 | MEN1 (0.59) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL21046041 | 0.84 | MEN1 (0.59) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL11065218 | 0.84 | MEN1 (0.59) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL8216269 | 0.84 | MEN1 (0.59) | MEN1KMT2ACYP4F2CYP4A11HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038072-B2 | Process for monoalkylation of C-H acidic methylene groups | DEGUSSA AG (DE) | 2006-05-02 | — | — | US | disclosed |
| US-20040054226-A1 | Process for monoalkylation of C-H acidic methylene groups | DEGUSSA AG | 2004-03-18 | — | — | US | disclosed |
| EP-1384706-A1 | Process for the monoalkylation of C-H acid methylene groups | Degussa AG (DE) | 2004-01-28 | — | — | EP | disclosed |