SCHEMBL60812

SCHEMBL60812

CCCCCCc1ccccc1Nc1cccc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 1/20 0.46
KDM4E B2RXH2 2/20 0.45
KMT2A Q03164 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
LIPG Q9Y5X9 1/20 0.45
CDC25B P30305 2/20 0.45
HPGD P15428 2/20 0.45
ALDH1A1 P00352 1/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
ATM Q13315 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CDC25A P30304 1/20 0.45
CDC25C P30307 1/20 0.45
NR5A2 O00482 1/20 0.42
EPHX1 P07099 1/20 0.41
CNR1 P21554 3/20 0.41
KCNH2 Q12809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258569 1.00 SLC16A3 (0.46) SLC16A3KDM4EKMT2AL3MBTL1LIPG
SCHEMBL58853 1.00 SLC16A3 (0.46) SLC16A3KDM4EKMT2AL3MBTL1LIPG
SCHEMBL60601 1.00 SLC16A3 (0.46) SLC16A3KDM4EKMT2AL3MBTL1LIPG
SCHEMBL3174756 1.00 SLC16A3 (0.46) SLC16A3KDM4EKMT2AL3MBTL1LIPG
SCHEMBL33526666 1.00 SLC16A3 (0.46) SLC16A3KDM4EKMT2AL3MBTL1LIPG
SCHEMBL284843 1.00 SLC16A3 (0.46) SLC16A3KDM4EKMT2AL3MBTL1LIPG
SCHEMBL9619173 1.00 SLC16A3 (0.46) SLC16A3KDM4EKMT2AL3MBTL1LIPG
SCHEMBL29448238 1.00 SLC16A3 (0.46) SLC16A3KDM4EKMT2AL3MBTL1LIPG
SCHEMBL29615063 1.00 SLC16A3 (0.46) SLC16A3KDM4EKMT2AL3MBTL1LIPG
SCHEMBL381831 0.98 HPGD (0.46) SLC16A3KDM4EKMT2AL3MBTL1LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 723 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119286570-A Preparation method of aromatic amine oligomeric coupling antioxidant and lubricating oil composition 中国石油化工股份有限公司 2025-01-10 CN claimed
CN-114752430-B Vacuum pump oil 出光兴产株式会社 2023-06-09 CN claimed
CN-109477029-B Vacuum pump oil 出光兴产株式会社 2022-06-17 CN claimed
CN-110392730-B Mineral oil base oil and vacuum pump oil 出光兴产株式会社 2022-04-26 CN claimed
US-9321721-B2 Kinase inhibitors ALLERGAN, INC. (US) 2016-04-26 US claimed
WO-2014138452-A1 KINASE INHIBITORS ALLERGAN, INC. (US) 2014-09-12 WO claimed
US-20140256819-A1 KINASE INHIBITORS ALLERGAN, INC. (US) 2014-09-11 US claimed
EP-0885192-B8 DIHYDROPYRIDINE-, PYRIDINE-, BENZOPYRAN- ONE- AND TRIAZOLOQUINAZOLINE DERIVATIVE, THEIR PREPARATION AND THEIR USE AS ADENOSINE RECEPTOR ANTAGONISTS US OF AMERICA REPRESENTED BY THE SECRETARY DEPT OF HEALTH AND HUMAN SERVICES (US) 2012-05-16 EP claimed
US-8163759-B2 Pyrazolo[1,5-A] pyrimidine compounds as CB1 receptor antagonist MITSUBISHI TANABE PHARMA CORPORATION (JP) 2012-04-24 US claimed
US-20110140049-A1 Corrosion Inhibitor Intensifier Compositions HALLIBURTON ENERGY SERVICES, INC. 2011-06-16 US claimed
US-5278165-A Oxazolyl imidazol[4,5-b]pyridin and pyrimidine compounds JANSSEN PHARMACEUTICA N.V. (BE) 1994-01-11 US claimed
US-5217980-A Antiallergens JANSSEN PHARMACEUTICA N.V. (BE) 1993-06-08 US claimed
US-5081152-A AZULENE DERIVATIVES AS THROMBOXANE A2 AND PROSTAGLANDIN ENDOPEROXIDE RECEPTOR ANTAGONIST KOTOBUKI SEIYAKU CO., LTD. (JP) 1992-01-14 US claimed
EP-0208621-B1 SUBSTITUTED AMIDES, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM RHONE-POULENC SANTE (FR) 1989-04-12 EP claimed
US-4819057-A METAL-ORGANIC FILMS-SEMICONDUCTOR JUNCTION KABUSHIKI KAISHA TOSHIBA (JP) 1989-04-04 US claimed
US-4720500-A N-1,8-naphthyridin-2-yl amides useful as immunostimulants RHONE-POULENC SANTE (FR) 1988-01-19 US claimed
EP-0239444-A1 Ferroelectric liquid crystal, process for its manufacture and its use in a liquid-crystal mixture THOMSON-CSF (FR) 1987-09-30 EP claimed
EP-0218422-A2 Semiconductor light-emitting element KABUSHIKI KAISHA TOSHIBA (JP) 1987-04-15 EP claimed
EP-0073143-A2 Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides Ryan, James Walter (US) 1983-03-02 EP claimed
US-3998834-A ANALGESICS JANSSEN PHARMACEUTICA N.V. (BE) 1976-12-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140256819-A1 KINASE INHIBITORS CDK1, MAP3K1, MAPK1 SLC16A3 4776/4885KDM4E 1440/4885KMT2A 2223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.