SCHEMBL60836

SCHEMBL60836

CC1=Cc2c(cccc2-c2ccccc2)[CH]1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
ADORA3 P0DMS8 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
ALDH1A1 P00352 3/20 0.34
HSD17B10 Q99714 2/20 0.34
CYP2A6 P11509 2/20 0.34
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP2B6 P20813 1/20 0.34
PLK4 O00444 1/20 0.33
MAPK9 P45984 1/20 0.33
LIMK1 P53667 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
AKT3 Q9Y243 1/20 0.33
METAP2 P50579 1/20 0.33
LMNA P02545 2/20 0.33
CA12 O43570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20548534 0.98 PDCD1 (0.38) PDCD1CD274ADORA3ADORA2AADORA1
SCHEMBL27509388 0.98 PDCD1 (0.38) PDCD1CD274ADORA3ADORA2AADORA1
SCHEMBL27478124 0.98 PDCD1 (0.38) PDCD1CD274ADORA3ADORA2AADORA1
SCHEMBL27441135 0.98 PDCD1 (0.38) PDCD1CD274ADORA3ADORA2AADORA1
SCHEMBL27496569 0.95 PDCD1 (0.36) PDCD1CD274ADORA3ADORA2AADORA1
SCHEMBL28475616 0.93 PDCD1 (0.35) PDCD1CD274ADORA3ADORA2AADORA1
SCHEMBL27537898 0.93 PDCD1 (0.35) PDCD1CD274ADORA3ADORA2AADORA1
SCHEMBL28815108 0.93 PDCD1 (0.35) PDCD1CD274ADORA3ADORA2AADORA1
SCHEMBL27516795 0.93 PDCD1 (0.35) PDCD1CD274ADORA3ADORA2AADORA1
SCHEMBL27476828 0.93 PDCD1 (0.35) PDCD1CD274ADORA3ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4393962-A1 CATALYST COMPOSITION AND APPLICATION THEREOF China Petroleum & Chemical Corporation (CN) 2024-07-03 EP claimed
EP-4388019-A1 MODULATING CO-MONOMER SELECTIVITY USING NON-COVALENT DISPERSION INTERACTIONS IN GROUP 4 OLEFIN POLYMERIZATION CATALYSTS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-06-26 EP claimed
CN-115894757-B Ethylene-enol copolymer and preparation method thereof 中国石油化工股份有限公司 2024-06-04 CN claimed
CN-118084987-A Silicon bridged neutral ligand-containing side arm single metallocene complex and application thereof 贝欧亿(山东)新材料有限公司 2024-05-28 CN claimed
CN-115894758-B Ethylene-cycloolefin copolymer and process for producing the same 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-117769573-A Regulation of comonomer selectivity in group 4 olefin polymerization catalysts using non-covalent dispersive interactions 切弗朗菲利浦化学公司 2024-03-26 CN claimed
US-11859041-B2 Modulating co-monomer selectivity using non-covalent dispersion interactions in group 4 olefin polymerization catalysts CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-01-02 US claimed
CN-117143274-A Catalyst composition, olefin polymerization process and use 中国石油化工股份有限公司 2023-12-01 CN claimed
CN-117143275-A Catalyst composition, olefin polymerization process and use 中国石油化工股份有限公司 2023-12-01 CN claimed
CN-117143276-A Catalyst composition, olefin polymerization process and use 中国石油化工股份有限公司 2023-12-01 CN claimed
US-5942459-A ALUMOXANE-FREE MIXTURE OF TRANSITION METAL METALLOCENE, ORGANOALUMINUM COMPOUND, BORIC ACID-CONTAINING POWDER MITSUBISHI CHEMICAL CORPORATION (JP) 1999-08-24 US claimed
CN-1216548-A Yttrium-containing metal complexes and olefin polymerization process DOW CHEMICAL CO (US) 1999-05-12 CN claimed
WO-1999015537-A1 TRANSITION METAL COMPOUND TARGOR GMBH (DE) 1999-04-01 WO claimed
EP-0901497-A1 YTTRIUM CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1999-03-17 EP claimed
EP-0728773-B1 Catalysts for olefin polymerization and a process for preparing olefin polymers therewith MITSUBISHI CHEM CORP (JP) 1998-11-04 EP claimed
US-5808122-A Organometallic compound HOECHST AKTIENGESELLSCHAFT (DE) 1998-09-15 US claimed
US-5726333-A POLYMERIZATION CATALYSTS HOECHST AG (DE) 1998-03-10 US claimed
WO-1997043294-A1 YTTRIUM CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1997-11-20 WO claimed
CN-1156997-A Dicyclopentadienyl diene complexes DOW CHEMICAL CO (US) 1997-08-13 CN claimed
EP-0728773-A1 Catalysts for olefin polymerization and a process for preparing olefin polymers therewith MITSUBISHI CHEMICAL CORPORATION (JP) 1996-08-28 EP claimed