SCHEMBL608453

SCHEMBL608453

CC(C)N(Cc1ccccc1)C(C)C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.54
ALDH1A1 P00352 2/20 0.54
SLC6A2 P23975 2/20 0.52
SLC6A4 P31645 2/20 0.52
SLC6A3 Q01959 2/20 0.52
ADRA2B P18089 1/20 0.52
ADRA2C P18825 1/20 0.52
HTR2A P28223 1/20 0.52
ADRA1A P35348 1/20 0.52
OPRK1 P41145 1/20 0.52
KCNH2 Q12809 1/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
AOC3 Q16853 1/20 0.50
HDAC1 Q13547 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
CARM1 Q86X55 1/20 0.48
PRMT6 Q96LA8 1/20 0.48
PRMT8 Q9NR22 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27658035 0.98 TSHR (0.52) TSHRALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL9990734 0.91 MEN1 (0.50) TSHRALDH1A1SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL3333913 0.89 MEN1 (0.49) TSHRALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL26267232 0.87 HDAC1 (0.59) TSHRALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL2662419 0.87 KMT2A (0.50) TSHRALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL24176560 0.85 TSHR (0.45) TSHRALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL14276380 0.85 TSHR (0.45) TSHRALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL24176562 0.85 TSHR (0.45) TSHRALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL8723999 0.82 CYP3A4 (0.44) TSHRALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL10558835 0.81 TSHR (0.50) TSHRALDH1A1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10472565-B2 Low temperature activator systems and methods for chemiluminescent reactions CYALUME TECHNOLOGIES, INC. (US) 2019-11-12 US claimed
EP-3004286-B1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS CYALUME TECH INC (US) 2019-08-28 EP claimed
CN-104192824-B Preparation method of nitrogen-doped ordered mesoporous carbon material 南京航空航天大学 2017-01-11 CN claimed
EP-3004286-A1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS Cyalume Technologies, Inc (US) 2016-04-13 EP claimed
US-9115305-B2 Broad temperature performance chemiluminescent systems and methods CYALUME TECHNOLOGIES, INC. (US) 2015-08-25 US claimed
CN-104192824-A Preparation method of nitrogen-doped ordered mesoporous carbon material UNIV NANJING AERONAUTICS 2014-12-10 CN claimed
US-20140356975-A1 LOW TEMPERATURE ACTIVATOR SYSTEMS AND METHODS FOR CHEMILUMINESCENT REACTIONS Cyalume Technologies (US) 2014-12-04 US claimed
US-20140353559-A1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS Cyalume Technologies (US) 2014-12-04 US claimed
WO-2014194332-A1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS Cyalume Technologies (US) 2014-12-04 WO claimed
CN-102432616-A Method for preparing L-prolinamide and intermediate thereof HEBEI BOLUNTE PHARMACEUTICAL CO LTD 2012-05-02 CN claimed
CN-118993824-A N-alkyl benzamide compound and synthesis method thereof 温州大学 2024-11-22 CN disclosed
EP-4139308-B1 PURINE DERIVATIVES AS DRUGS FOR THE TREATMENT OF NEONATAL HYPOXIA-ISCHEMIA BRAIN INJURY AND RELATED DISEASES COMMISSARIAT ENERGIE ATOMIQUE (FR) 2024-07-17 EP disclosed
US-11996557-B2 Direct regeneration of lithium ion cathodes by ionothermal relithiation UT-BATTELLE, LLC (US) 2024-05-28 US disclosed
US-11833493-B2 Metal catalyst, method of C-N coupling using the same and applications of the same BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2023-12-05 US disclosed
US-20220376240-A1 DIRECT REGENERATION OF LITHIUM ION CATHODES BY IONOTHERMAL RELITHIATION U. S. DEPARTMENT OF ENERGY 2022-11-24 US disclosed
EP-0147879-A1 Process for the preparation of a hydroxylamine AKZO N.V. (NL) 1985-07-10 EP disclosed
EP-0122232-A1 20-Spiroxanes and analogues with open ring E, process for their preparation and pharmaceutical compositions CIBA-GEIGY AG (CH) 1984-10-17 EP disclosed
EP-0003383-B1 4-AMINO-3-SULFONAMIDO PYRIDINE DERIVATIVES A. CHRISTIAENS SOCIETE ANONYME (BE) 1983-02-09 EP disclosed
EP-0003383-A2 4-Amino-3-sulfonamido pyridine derivatives A. CHRISTIAENS SOCIETE ANONYME (BE) 1979-08-08 EP disclosed
US-4069252-A Process for the preparation of certain acyl cyanide compounds BAYER AKTIENGESELLSCHAFT (DT) 1978-01-17 US disclosed