⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL11597664 | 0.94 | — | — | |
| SCHEMBL5801651 | 0.69 | — | — | |
| SCHEMBL4649379 | 0.65 | — | — | |
| SCHEMBL884315 | 0.63 | — | — | |
| SCHEMBL11277151 | 0.61 | — | — | |
| SCHEMBL3077092 | 0.59 | — | — | |
| SCHEMBL11243073 | 0.51 | — | — | |
| SCHEMBL432911 | 0.51 | — | — | |
| SCHEMBL13341976 | 0.50 | — | — | |
| SCHEMBL1887298 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240271119-A1 | METHODS OF PERIPLASMIC PHAGE-ASSISTED CONTINUOUS EVOLUTION | THE BROAD INSTITUTE, INC. (US) | 2024-08-15 | — | — | US | claimed |
| EP-4377455-A1 | METHODS OF PERIPLASMIC PHAGE-ASSISTED CONTINUOUS EVOLUTION | The Broad Institute Inc. (US) | 2024-06-05 | — | — | EP | claimed |
| WO-2023010050-A1 | METHODS OF PERIPLASMIC PHAGE-ASSISTED CONTINUOUS EVOLUTION | THE BROAD INSTITUTE, INC. (US) | 2023-02-02 | — | — | WO | claimed |
| WO-2021062048-A2 | METHODS AND SYSTEMS FOR MODULATING HEPATIC GABA PRODUCTION OR RELEASE TO ALTER FOOD INTAKE IN MONOGASTRIC SPECIES | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-04-01 | — | — | WO | claimed |
| EP-3199630-B1 | CONTINUOUS DIRECTED EVOLUTION OF PROTEINS AND NUCLEIC ACIDS | HARVARD COLLEGE (US) | 2019-05-08 | — | — | EP | claimed |
| US-9771574-B2 | Apparatus for continuous directed evolution of proteins and nucleic acids | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-09-26 | — | — | US | claimed |
| EP-3199630-A1 | CONTINUOUS DIRECTED EVOLUTION OF PROTEINS AND NUCLEIC ACIDS | President and Fellows of Harvard College (US) | 2017-08-02 | — | — | EP | claimed |
| EP-2342336-B1 | CONTINUOUS DIRECTED EVOLUTION OF PROTEINS AND NUCLEIC ACIDS | HARVARD COLLEGE (US) | 2016-12-14 | — | — | EP | claimed |
| WO-2016168631-A1 | VECTOR-BASED MUTAGENESIS SYSTEM | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-10-20 | — | — | WO | claimed |
| WO-2016077052-A9 | EVOLUTION OF PROTEASES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-07-21 | — | — | WO | claimed |
| CN-102370967-A | Novel application of IL-1Ra (interleukin-1 receptor antagonist) and tumor treatment medicinal composition kit thereof | UNIV SHANGHAI JIAOTONG | 2012-03-14 | — | — | CN | claimed |
| EP-2421523-A1 | METHOD OF TREATING OR PREVENTING A CONVULSIVE DISORDER IN A PATIENT IN NEED THEREOF | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2012-02-29 | — | — | EP | claimed |
| US-20110177495-A1 | CONTINUOUS DIRECTED EVOLUTION OF PROTEINS AND NUCLEIC ACIDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-07-21 | — | — | US | claimed |
| EP-2342336-A2 | CONTINUOUS DIRECTED EVOLUTION OF PROTEINS AND NUCLEIC ACIDS | President and Fellows of Harvard College (US) | 2011-07-13 | — | — | EP | claimed |
| WO-2010121969-A1 | METHOD OF TREATING OR PREVENTING A CONVULSIVE DISORDER IN A PATIENT IN NEED THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2010-10-28 | — | — | WO | claimed |
| US-20100184707-A1 | ANTICONVULSIVE PHARMACEUTICAL COMPOSITIONS | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2010-07-22 | — | — | US | claimed |
| EP-2167068-A2 | ANTICONVULSIVE PHARMACEUTICAL COMPOSITIONS | Inserm-Institut National De La Sante Et De La Recherche Medicale (FR) | 2010-03-31 | — | — | EP | claimed |
| WO-2010028347-A2 | CONTINUOUS DIRECTED EVOLUTION OF PROTEINS AND NUCLEIC ACIDS | PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) | 2010-03-11 | — | — | WO | claimed |
| WO-2009004082-A2 | ANTICONVULSIVE PHARMACEUTICAL COMPOSITIONS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2009-01-08 | — | — | WO | claimed |
| EP-2011491-A1 | Anticonvulsive pharmaceutical compositions | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-01-07 | — | — | EP | claimed |