Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087260 | 0.96 | CYP1A2 (0.59) | MAPK1CYP1A2LMNAAGTR1KDM4E | |
| SCHEMBL17908100 | 0.87 | TSHR (0.64) | MAPK1CYP1A2LMNAAGTR1KDM4E | |
| SCHEMBL17908051 | 0.87 | TSHR (0.64) | MAPK1CYP1A2LMNAAGTR1KDM4E | |
| SCHEMBL2743809 | 0.85 | MEN1 (0.63) | MAPK1CYP1A2LMNAAGTR1KDM4E | |
| SCHEMBL30989216 | 0.85 | MEN1 (0.63) | MAPK1CYP1A2LMNAAGTR1KDM4E | |
| SCHEMBL6087272 | 0.84 | CYP1A2 (0.55) | MAPK1CYP1A2LMNAAGTR1KDM4E | |
| SCHEMBL9448494 | 0.84 | KDM4E (0.55) | CYP1A2AGTR1KDM4E | |
| SCHEMBL4685164 | 0.84 | KDM4E (0.55) | CYP1A2AGTR1KDM4E | |
| SCHEMBL4685166 | 0.84 | KDM4E (0.55) | CYP1A2AGTR1KDM4E | |
| SCHEMBL3842541 | 0.83 | MAPK1 (0.68) | MAPK1CYP1A2TSHRCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015160842-A1 | METHODS AND FORMULATIIONS OF CAPSAICINOIDS AND CAPSINOIDS | FLEX PHARMA, INC. (US) | 2015-10-22 | — | — | WO | claimed |
| US-5041653-A | Antitumor agents | SRI INTERNATIONAL (US) | 1991-08-20 | — | — | US | claimed |
| WO-1986006628-A1 | BENZAMIDE AND NICOTINAMIDE RADIOSENSITIZERS | SRI INTERNATIONAL (US) | 1986-11-20 | — | — | WO | claimed |
| US-20190038573-A1 | ION CHANNEL ACTIVATORS AND METHODS OF USE | CLIFF-CARTWRIGHT CORPORATION | 2019-02-07 | — | — | US | disclosed |
| EP-3131541-A1 | ION CHANNEL ACTIVATORS AND METHODS OF USE | Flex Pharma, Inc. (US) | 2017-02-22 | — | — | EP | disclosed |
| US-20170042834-A1 | ION CHANNEL ACTIVATORS AND METHODS OF USE | CLIFF-CARTWRIGHT CORPORATION | 2017-02-16 | — | — | US | disclosed |
| WO-2015160843-A1 | ION CHANNEL ACTIVATORS AND METHODS OF USE | FLEX PHARMA, INC. (US) | 2015-10-22 | — | — | WO | disclosed |
| WO-2015160842-A1 | METHODS AND FORMULATIIONS OF CAPSAICINOIDS AND CAPSINOIDS | FLEX PHARMA, INC. (US) | 2015-10-22 | — | — | WO | disclosed |
| US-7067552-B2 | Radiosensitizing taxanes and their pharmaceutical preparations | FLORIDA STATE UNIVERSITY (US) | 2006-06-27 | — | — | US | disclosed |
| US-20020040155-A1 | Radiosensitizing taxanes and their pharmaceutical preparations | FLORIDA STATE UNIVERSITY | 2002-04-04 | — | — | US | disclosed |
| EP-0956016-A4 | PHARMACEUTICAL COMPOUNDS COMPRISING POLYAMINES SUBSTITUTED WITH ELECTRON-AFFINIC GROUPS | UNIV FLORIDA STATE (US) | 2001-11-14 | — | — | EP | disclosed |
| WO-1998014190-A9 | PHARMACEUTICAL COMPOUNDS COMPRISING POLYAMINES SUBSTITUTED WITH ELECTRON-AFFINIC GROUPS | — | 1998-07-30 | — | — | WO | disclosed |
| WO-1998014190-A1 | PHARMACEUTICAL COMPOUNDS COMPRISING POLYAMINES SUBSTITUTED WITH ELECTRON-AFFINIC GROUPS | FLORIDA STATE UNIVERSITY (US) | 1998-04-09 | — | — | WO | disclosed |
| WO-1997009979-A9 | RADIOSENSITIZING TAXANES AND THEIR PHARMACEUTICAL PREPARATIONS | — | 1997-06-05 | — | — | WO | disclosed |
| WO-1997009979-A1 | RADIOSENSITIZING TAXANES AND THEIR PHARMACEUTICAL PREPARATIONS | FLORIDA STATE UNIVERSITY (US) | 1997-03-20 | — | — | WO | disclosed |
| US-5221692-A | Antinociceptives | NATIONAL SCIENCE COUNCIL (TW) | 1993-06-22 | — | — | US | disclosed |
| US-5215738-A | Used for destroying hypoxic tumor cells | SRI INTERNATIONAL (US) | 1993-06-01 | — | — | US | disclosed |
| US-5041653-A | Antitumor agents | SRI INTERNATIONAL (US) | 1991-08-20 | — | — | US | disclosed |
| US-5032617-A | Antitumor agents | SRI INTERNATIONAL (US) | 1991-07-16 | — | — | US | disclosed |
| WO-1986006628-A1 | BENZAMIDE AND NICOTINAMIDE RADIOSENSITIZERS | SRI INTERNATIONAL (US) | 1986-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040155-A1 | Radiosensitizing taxanes and their pharmaceutical preparations | TOP2A, XPA, TP53 | MAPK1 4504/4885CYP1A2 2445/4885LMNA 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.