Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 3/20 | 0.33 |
| ▸ | TPH2 | Q8IWU9 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086438 | 0.95 | GRIN1 (0.39) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6086706 | 0.94 | GRIN1 (0.39) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7073497 | 0.91 | GRIN1 (0.35) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7844956 | 0.88 | GRIN1 (0.35) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7847019 | 0.87 | GRIN1 (0.34) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2471003 | 0.82 | GRIN1 (0.42) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2465342 | 0.82 | SMN1; SMN2 (0.34) | MEN1KMT2ASMN1; SMN2PKMTDP1 | |
| SCHEMBL6087421 | 0.81 | SMN1; SMN2 (0.37) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7847397 | 0.81 | GRIN1 (0.43) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7759911 | 0.80 | SMN1; SMN2 (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |
| EP-1100786-B1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2004-07-21 | — | — | EP | disclosed |