⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577278 | 1.00 | — | — | |
| SCHEMBL608767 | 1.00 | — | — | |
| SCHEMBL2025147 | 0.79 | MAOB (0.46) | — | |
| SCHEMBL2025150 | 0.79 | MAOB (0.46) | — | |
| SCHEMBL922284 | 0.79 | MAOB (0.46) | — | |
| SCHEMBL6846425 | 0.77 | — | — | |
| SCHEMBL9454282 | 0.77 | DHODH (0.32) | — | |
| SCHEMBL9454288 | 0.77 | DHODH (0.32) | — | |
| SCHEMBL3237274 | 0.77 | CYP2C19 (0.34) | — | |
| SCHEMBL9454389 | 0.77 | HTR2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080085893-A1 | MATRIX METALLOPROTEASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-10 | — | — | US | claimed |
| US-20070161701-A1 | 4-oxo-4,5-dihydro-furan-2-carboxylic acid derivatives and methods of treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. | 2007-07-12 | — | — | US | claimed |
| JP-2007512346-A | — | — | 2007-05-17 | — | — | JP | claimed |
| US-20070093545-A1 | 4-Oxo-4,5-dihydro-furan-2-carboxylic acid derivatives and methods of treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. (US) | 2007-04-26 | — | — | US | claimed |
| CN-1882557-A | 4-oxo-4,5-dihydro-furan-2-carboxylic and acid derivatives and methods of treatment of metabolic-related disorders thereof | ARENA PHARM INC (US) | 2006-12-20 | — | — | CN | claimed |
| EP-1701947-A2 | 4-OXO-4,5-DIHYDRO-FURAN-2-CARBOXYLIC AND ACID DERIVATIVES AND METHODS OF TREATMENT OF METABOLIC-RELATED DISORDERS THEREOF | Arena Pharmaceuticals, Inc. (US) | 2006-09-20 | — | — | EP | claimed |
| WO-2005051937-A2 | 4-OXO-4,5-DIHYDRO-FURAN-2-CARBOXYLIC AND ACID DERIVATIVES AND METHODS OF TREATMENT OF METABOLIC-RELATED DISORDERS THEREOF | ARENA PHARMACEUTICALS, INC. (US) | 2005-06-09 | — | — | WO | claimed |
| WO-2024143964-A1 | CURING AGENT COMPOSITION AND CURABLE COMPOSITION CONTAINING SAME | 코오롱인더스트리 주식회사 | 2024-07-04 | — | — | WO | disclosed |
| CN-109096318-B | Method for preparing organic boron compound and beta-hydroxy compound under catalysis of copper ion-loaded Y-type molecular sieve | 湖北工程学院 | 2020-11-24 | — | — | CN | disclosed |
| EP-3239183-B1 | MODIFIED CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION CONTAINING SAID POLYMER | SUMITOMO CHEMICAL CO (JP) | 2020-03-11 | — | — | EP | disclosed |
| US-10118973-B2 | Modified conjugated diene polymer, and polymer composition containing said polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-11-06 | — | — | US | disclosed |
| EP-2927218-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-07-04 | — | — | EP | disclosed |
| US-20170369599-A1 | MODIFIED CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION CONTAINING SAID POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-12-28 | — | — | US | disclosed |
| CN-1242771-A | Ketone derivatives and medicinal use thereof | TORAY INDUSTRIES (JP) | 2000-01-26 | — | — | CN | disclosed |
| CN-1187492-A | Catalyst for preparing functional polymer | HOECHST AG (DE) | 1998-07-15 | — | — | CN | disclosed |
| US-5389620-A | Bronchodilation agent, vasodilation | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| US-5234946-A | Anticholesterol, antilipemic | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0318860-B1 | SUBSTITUTED ALKYLAMINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| CN-1037141-A | The alkylamine derivative that replaces | BANYU PHARMA CO LTD (JP) | 1989-11-15 | — | — | CN | disclosed |
| EP-0318860-A2 | Substituted alkylamine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |