Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 14/20 | 0.41 |
| ▸ | KDR | P35968 | 9/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 3/20 | 0.36 |
| ▸ | YES1 | P07947 | 3/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087937 | 1.00 | SRC (0.41) | SRCKDRPDGFRBFGFR1ALK | |
| SCHEMBL6092229 | 0.91 | SRC (0.46) | SRCKDRPDGFRBFGFR1ALK | |
| SCHEMBL6092224 | 0.91 | SRC (0.46) | SRCKDRPDGFRBFGFR1ALK | |
| SCHEMBL6090710 | 0.83 | SRC (0.41) | SRCKDRPDGFRBFGFR1FYN | |
| SCHEMBL6090717 | 0.83 | SRC (0.41) | SRCKDRPDGFRBFGFR1FYN | |
| SCHEMBL6089940 | 0.83 | SRC (0.42) | SRCKDRPDGFRBFGFR1ALK | |
| SCHEMBL6089946 | 0.83 | SRC (0.42) | SRCKDRPDGFRBFGFR1ALK | |
| SCHEMBL6089301 | 0.82 | SRC (0.44) | SRCKDRPDGFRBFGFR1ALK | |
| SCHEMBL6089309 | 0.82 | SRC (0.44) | SRCKDRPDGFRBFGFR1ALK | |
| SCHEMBL6088090 | 0.82 | SRC (0.42) | SRCKDRPDGFRBFGFR1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |