Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088406 | 1.00 | KDR (0.43) | KDRCHEK1SRC | |
| SCHEMBL6090092 | 0.92 | KDR (0.43) | KDRCHEK1SRC | |
| SCHEMBL6090102 | 0.92 | KDR (0.43) | KDRCHEK1SRC | |
| SCHEMBL6090358 | 0.87 | KDR (0.42) | KDRCHEK1 | |
| SCHEMBL6091226 | 0.85 | KDR (0.62) | KDRCHEK1SRC | |
| SCHEMBL6091093 | 0.85 | KDR (0.43) | KDRCHEK1SRC | |
| SCHEMBL6091103 | 0.85 | KDR (0.43) | KDRCHEK1SRC | |
| SCHEMBL6091244 | 0.85 | KDR (0.62) | KDRCHEK1SRC | |
| SCHEMBL6088180 | 0.84 | KDR (0.37) | KDRCHEK1 | |
| SCHEMBL6088165 | 0.84 | KDR (0.37) | KDRCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |