Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4976402 | 0.92 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL4972852 | 0.91 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL4972720 | 0.91 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL4975052 | 0.90 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL4917987 | 0.88 | TRPV1 (0.72) | TRPV1 | |
| SCHEMBL4919573 | 0.87 | TRPV1 (0.73) | TRPV1 | |
| SCHEMBL4915946 | 0.86 | TRPV1 (0.60) | TRPV1 | |
| SCHEMBL4973824 | 0.85 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL4908637 | 0.84 | TRPV1 (0.58) | TRPV1 | |
| SCHEMBL4972370 | 0.84 | TRPV1 (0.57) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074799-B2 | Substituted quinazolin-4-ylamine analogues | NEUROGEN CORPORATION (US) | 2006-07-11 | — | — | US | claimed |