Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.58 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089481 | 1.00 | CYSLTR1 (0.58) | CYSLTR1GPBAR1CYSLTR2PTGER1PTGER4 | |
| SCHEMBL6089132 | 0.86 | CYSLTR1 (0.62) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6089807 | 0.83 | CYSLTR1 (0.66) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6088435 | 0.83 | CYSLTR1 (0.66) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL7716691 | 0.80 | CYSLTR1 (0.88) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL7809016 | 0.80 | PTGER4 (0.70) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL7809010 | 0.80 | PTGER4 (0.70) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL6089926 | 0.79 | CYSLTR1 (0.61) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6091338 | 0.79 | CYSLTR1 (0.61) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6088484 | 0.79 | CYSLTR1 (0.69) | CYSLTR1GPBAR1CYSLTR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |