Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092230 | 0.91 | KDR (0.49) | KDRCHEK1 | |
| SCHEMBL6092241 | 0.91 | KDR (0.49) | KDRCHEK1 | |
| SCHEMBL6091487 | 0.89 | KDR (0.48) | KDRCHEK1 | |
| SCHEMBL6091474 | 0.89 | KDR (0.48) | KDRCHEK1 | |
| SCHEMBL6087958 | 0.88 | KDR (0.56) | KDRCHEK1 | |
| SCHEMBL6091422 | 0.88 | KDR (0.56) | KDRCHEK1 | |
| SCHEMBL6088681 | 0.87 | KDR (0.55) | KDRCHEK1 | |
| SCHEMBL6091184 | 0.84 | KDR (0.67) | KDRCHEK1 | |
| SCHEMBL6091199 | 0.84 | KDR (0.67) | KDRCHEK1 | |
| SCHEMBL6090670 | 0.83 | KDR (0.47) | KDRCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |
| EP-1218373-A2 | 2-PYRAZOLIN-5-ONES AS TYROSINE KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001009121-A2 | 2-PYRAZOLIN-5-ONES_AS TYROSINE KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-08 | — | — | WO | disclosed |