Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 16/20 | 0.48 |
| ▸ | SRC | P12931 | 7/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.48 |
| ▸ | LCK | P06239 | 3/20 | 0.48 |
| ▸ | FYN | P06241 | 3/20 | 0.48 |
| ▸ | YES1 | P07947 | 3/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090848 | 0.93 | KDR (0.52) | KDRSRCFGFR1LCKFYN | |
| SCHEMBL6088556 | 0.92 | KDR (0.51) | KDRSRCFGFR1LCKFYN | |
| SCHEMBL6088867 | 0.90 | KDR (0.51) | KDRSRCFGFR1LCKFYN | |
| SCHEMBL6089168 | 0.87 | SRC (0.49) | KDRSRCFGFR1LCKFYN | |
| SCHEMBL6089156 | 0.87 | SRC (0.49) | KDRSRCFGFR1LCKFYN | |
| SCHEMBL6092382 | 0.86 | SRC (0.51) | KDRSRCFGFR1LCKFYN | |
| SCHEMBL6092373 | 0.86 | SRC (0.51) | KDRSRCFGFR1LCKFYN | |
| SCHEMBL6089561 | 0.86 | SRC (0.49) | KDRSRCFGFR1LCKFYN | |
| SCHEMBL6089569 | 0.86 | SRC (0.49) | KDRSRCFGFR1LCKFYN | |
| SCHEMBL6089694 | 0.85 | KDR (0.50) | KDRSRCFGFR1LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |