Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089654 | 1.00 | ALK (0.38) | ALKMTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL6090221 | 0.89 | KDR (0.45) | KDM4EALDH1A1PKMKDREGFR | |
| SCHEMBL6090238 | 0.89 | KDR (0.45) | KDM4EALDH1A1PKMKDREGFR | |
| SCHEMBL6089553 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1PKMKDREGFR | |
| SCHEMBL6089562 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1PKMKDREGFR | |
| SCHEMBL6089917 | 0.85 | ALK (0.38) | ALKKDM4EALDH1A1PKMKDR | |
| SCHEMBL6089928 | 0.85 | ALK (0.38) | ALKKDM4EALDH1A1PKMKDR | |
| SCHEMBL6092188 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1PKMKDREGFR | |
| SCHEMBL6092182 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1PKMKDREGFR | |
| SCHEMBL6092216 | 0.82 | EGFR (0.40) | KDM4EALDH1A1PKMEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |