Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.58 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.56 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089372 | 0.87 | CYSLTR1 (0.62) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6582234 | 0.85 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL7559431 | 0.83 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6089220 | 0.83 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6089814 | 0.83 | CYSLTR1 (0.65) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6088575 | 0.82 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6088899 | 0.81 | GPBAR1 (0.61) | CYSLTR1CYSLTR2GPBAR1ALOX5AP | |
| SCHEMBL6088840 | 0.80 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6090813 | 0.79 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6587609 | 0.79 | GPBAR1 (0.58) | CYSLTR1CYSLTR2GPBAR1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |