Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3588111 | 1.00 | TSHR (0.32) | TSHR | |
| SCHEMBL3588108 | 1.00 | TSHR (0.32) | TSHR | |
| SCHEMBL3226544 | 0.86 | TSHR (0.32) | TSHR | |
| SCHEMBL4254553 | 0.81 | — | — | |
| SCHEMBL6416325 | 0.81 | — | — | |
| SCHEMBL4254548 | 0.81 | — | — | |
| SCHEMBL3551263 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL3551261 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL3584679 | 0.79 | TP53 (0.36) | — | |
| SCHEMBL6415305 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018997-B2 | Tricyclic 6-alkylidene-penems as β-lactamase inhibitors | WYETH (US) | 2006-03-28 | — | — | US | claimed |