Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 14/20 | 0.45 |
| ▸ | FCER2 | P06734 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090500 | 1.00 | KDR (0.45) | KDRFCER2SYKMEN1KMT2A | |
| SCHEMBL6088407 | 0.82 | KMT2A (0.57) | KDRSYKMEN1KMT2AITGA4 | |
| SCHEMBL6090976 | 0.79 | KDR (0.47) | KDRFCER2SYKMEN1KMT2A | |
| SCHEMBL6090973 | 0.79 | KDR (0.47) | KDRFCER2SYKMEN1KMT2A | |
| SCHEMBL6089894 | 0.77 | KDR (0.62) | KDRFCER2SYKMEN1KMT2A | |
| SCHEMBL6090746 | 0.76 | KDR (0.72) | KDR | |
| SCHEMBL6090763 | 0.76 | KDR (0.72) | KDR | |
| SCHEMBL7490866 | 0.75 | DYRK1A (0.40) | KDRMEN1KMT2A | |
| SCHEMBL6088768 | 0.73 | KDR (0.40) | KDRSYKMEN1KMT2AITGA4 | |
| SCHEMBL6091656 | 0.72 | KDR (0.51) | KDRSYKMEN1KMT2AITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |