Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 3/20 | 0.34 |
| ▸ | FYN | P06241 | 3/20 | 0.34 |
| ▸ | YES1 | P07947 | 3/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.34 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.34 |
| ▸ | TLK1 | Q9UKI8 | 2/20 | 0.34 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090661 | 1.00 | KDR (0.47) | KDRCHEK1HSD17B10FGFR1PDGFRB | |
| SCHEMBL6088205 | 0.87 | KDR (0.63) | KDRCHEK1HSD17B10FGFR1PDGFRB | |
| SCHEMBL6088221 | 0.87 | KDR (0.63) | KDRCHEK1HSD17B10FGFR1PDGFRB | |
| SCHEMBL6089581 | 0.85 | KDR (0.43) | KDRCHEK1HSD17B10FGFR1PDGFRB | |
| SCHEMBL6089572 | 0.85 | KDR (0.43) | KDRCHEK1HSD17B10FGFR1PDGFRB | |
| SCHEMBL6088946 | 0.84 | KDR (0.44) | KDRCHEK1HSD17B10FGFR1PDGFRB | |
| SCHEMBL6088933 | 0.84 | KDR (0.44) | KDRCHEK1HSD17B10FGFR1PDGFRB | |
| SCHEMBL6090742 | 0.84 | KDR (0.43) | KDRCHEK1HSD17B10FGFR1PDGFRB | |
| SCHEMBL6090757 | 0.84 | KDR (0.43) | KDRCHEK1HSD17B10FGFR1PDGFRB | |
| SCHEMBL6090083 | 0.82 | KDR (0.45) | KDRCHEK1HSD17B10FGFR1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |