Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.55 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089372 | 0.91 | CYSLTR1 (0.62) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6088921 | 0.90 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL6089840 | 0.87 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL6088899 | 0.86 | GPBAR1 (0.61) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL6089262 | 0.86 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL6088575 | 0.85 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL4841922 | 0.85 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6089203 | 0.84 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL5726739 | 0.84 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL6089083 | 0.83 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2GPBAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |