Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.66 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.66 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089416 | 0.88 | CYSLTR1 (0.55) | CYSLTR1GPBAR1CYSLTR2KDM4EMEN1 | |
| SCHEMBL5725146 | 0.81 | CYSLTR1 (0.67) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL422355 | 0.81 | CYSLTR1 (1.00) | CYSLTR1GPBAR1CYSLTR2KDM4EMEN1 | |
| SCHEMBL30444017 | 0.81 | CYSLTR1 (1.00) | CYSLTR1GPBAR1CYSLTR2KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7006935 | 0.80 | CYSLTR1 (0.97) | CYSLTR1GPBAR1CYSLTR2KDM4EMEN1 | |
| SCHEMBL6091338 | 0.77 | CYSLTR1 (0.61) | CYSLTR1GPBAR1CYSLTR2KDM4EMEN1 | |
| SCHEMBL6090583 | 0.77 | CYSLTR1 (0.58) | CYSLTR1GPBAR1CYSLTR2KDM4EMEN1 | |
| SCHEMBL10484526 | 0.76 | CYSLTR1 (0.81) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL6088989 | 0.76 | CYSLTR1 (0.61) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7716691 | 0.76 | CYSLTR1 (0.88) | CYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |