Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091301 | 1.00 | KDR (0.41) | KDRCHEK1PDGFRBFGFR1TLK2 | |
| SCHEMBL6092233 | 0.88 | KDR (0.55) | KDRCHEK1PDGFRBFGFR1HRH3 | |
| SCHEMBL6092240 | 0.88 | KDR (0.55) | KDRCHEK1PDGFRBFGFR1HRH3 | |
| SCHEMBL6087234 | 0.86 | KDR (0.42) | KDRCHEK1PDGFRBFGFR1 | |
| SCHEMBL6087239 | 0.86 | KDR (0.42) | KDRCHEK1PDGFRBFGFR1 | |
| SCHEMBL6088693 | 0.86 | KDR (0.38) | KDRCHEK1PDGFRBFGFR1 | |
| SCHEMBL6088686 | 0.86 | KDR (0.38) | KDRCHEK1PDGFRBFGFR1 | |
| SCHEMBL6088243 | 0.85 | KDR (0.38) | KDRCHEK1PDGFRBFGFR1 | |
| SCHEMBL6088252 | 0.85 | KDR (0.38) | KDRCHEK1PDGFRBFGFR1 | |
| SCHEMBL6089245 | 0.85 | KDR (0.38) | KDRCHEK1PDGFRBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |