Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.67 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.67 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.67 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.67 |
| ▸ | FAP | Q12884 | 2/20 | 0.67 |
| ▸ | TACR1 | P25103 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 3/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29541867 | 1.00 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8862702 | 1.00 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6933624 | 1.00 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| Bromide SCHEMBL7274107 | 0.99 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| Hydrochloric Acid SCHEMBL6348160 | 0.99 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| Trifluoroacetic Acid SCHEMBL9551620 | 0.94 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL5900809 | 0.91 | ACE (0.70) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL3726263 | 0.91 | ACE (0.70) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7375090 | 0.91 | ACE (0.70) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6436643 | 0.91 | ACE (0.70) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112590-B2 | Thrombin inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2006-09-26 | — | — | US | disclosed |