Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.73 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.73 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716691 | 0.91 | CYSLTR1 (0.88) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6089805 | 0.89 | CYSLTR1 (0.74) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL7711072 | 0.87 | GPBAR1 (0.80) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL7010090 | 0.87 | CYSLTR1 (0.84) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL422355 | 0.85 | CYSLTR1 (1.00) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL30444017 | 0.85 | CYSLTR1 (1.00) | CYSLTR1GPBAR1CYSLTR2 | |
| Hydrochloric Acid SCHEMBL7006935 | 0.84 | CYSLTR1 (0.97) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7715799 | 0.84 | CYSLTR1 (0.86) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7452285 | 0.83 | CYSLTR1 (0.77) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL9023239 | 0.83 | CYSLTR1 (0.82) | CYSLTR1GPBAR1CYSLTR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |