Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.71 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.53 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.51 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092383 | 1.00 | KDR (0.71) | KDRALKMEN1CRHBPKMT2A | |
| SCHEMBL6088397 | 0.79 | KMT2A (0.64) | KDRALKMEN1CRHBPKMT2A | |
| SCHEMBL6088402 | 0.79 | KMT2A (0.64) | KDRALKMEN1CRHBPKMT2A | |
| SCHEMBL6091700 | 0.78 | KDR (0.65) | KDRALKMEN1CRHBPKMT2A | |
| SCHEMBL6091704 | 0.78 | KDR (0.65) | KDRALKMEN1CRHBPKMT2A | |
| SCHEMBL6091472 | 0.77 | KDR (0.67) | KDRALKMEN1CRHBPKMT2A | |
| SCHEMBL6091485 | 0.77 | KDR (0.67) | KDRALKMEN1CRHBPKMT2A | |
| SCHEMBL6090428 | 0.77 | KDR (0.73) | KDRALKMEN1CRHBPKMT2A | |
| SCHEMBL6088819 | 0.77 | KDR (0.64) | KDRALKMEN1CRHBPKMT2A | |
| SCHEMBL6090432 | 0.77 | KDR (0.73) | KDRALKMEN1CRHBPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |