SCHEMBL6093294

SCHEMBL6093294

COc1ccc(CC(=O)NC(CCN(C)C)c2ccc(Cl)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 19/20 1.00
CNR2 P34972 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5457616 0.99 UTS2R (0.98) UTS2RCNR2
SCHEMBL6092298 0.90 UTS2R (1.00) UTS2R
Hydrochloric Acid SCHEMBL5464571 0.89 UTS2R (0.98) UTS2R
Hydrochloric Acid SCHEMBL5461098 0.88 UTS2R (0.98) UTS2R
Hydrochloric Acid SCHEMBL5464562 0.86 UTS2R (0.98) UTS2RCNR2
Oxalic Acid SCHEMBL5465026 0.85 UTS2R (0.95) UTS2RCNR2
Hydrochloric Acid SCHEMBL5464581 0.83 UTS2R (0.98) UTS2RCNR2
Hydrochloric Acid SCHEMBL5452768 0.82 UTS2R (0.81) UTS2R
SCHEMBL4732603 0.82 UTS2R (1.00) UTS2R
Oxalic Acid SCHEMBL5456558 0.82 UTS2R (0.93) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006135694-A2 UII-MODULATING COMPOUNDS AND THEIR USE ACADIA PHARMACEUTICALS INC. (US) 2006-12-21 WO disclosed