Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.47 |
| ▸ | CDK4 | P11802 | 2/20 | 0.47 |
| ▸ | IDH1 | O75874 | 6/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6096360 | 0.86 | SMG1 (0.49) | CDK2CDK4IDH1CDC7CDK19 | |
| SCHEMBL6094300 | 0.75 | SMG1 (0.61) | CDK2CDK4CCNA2CDK9CDK5 | |
| SCHEMBL6095641 | 0.75 | SMG1 (0.61) | CDK2CDK4CCNA2CDK9CDK5 | |
| SCHEMBL6095791 | 0.75 | SMG1 (0.61) | CDK2CDK4CCNA2CDK9CDK5 | |
| SCHEMBL6095910 | 0.75 | SMG1 (0.63) | CDK2CDK4IDH1CLK2DYRK1A | |
| SCHEMBL2282503 | 0.73 | CDK2 (0.61) | CDK2CDK4CCNA2CCNA1GSK3B | |
| SCHEMBL2278872 | 0.73 | CDK2 (0.61) | CDK2CDK4CDC7CCNA2CCNA1 | |
| SCHEMBL2287024 | 0.72 | CDK2 (0.59) | CDK2CDK4CDC7CCNA2EPHB4 | |
| SCHEMBL2282024 | 0.72 | CDK2 (0.56) | CDK2CDK4CDC7PIK3CAPIK3CG | |
| SCHEMBL2288845 | 0.71 | CDK2 (0.57) | CDK2CDK4CDC7EPHB4CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074787-B2 | Microbiocidal N-phenyl-N-[4-(4-pyridyl-2-pyrimidin-2-yl]-amine derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2006-07-11 | — | — | US | disclosed |