Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.55 |
| ▸ | MMP1 | P03956 | 8/20 | 0.44 |
| ▸ | MMP2 | P08253 | 8/20 | 0.44 |
| ▸ | MMP9 | P14780 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6095971 | 1.00 | SNCA (0.55) | SNCAMMP1MMP2MMP9MEN1 | |
| SCHEMBL6138731 | 0.89 | MAPT (0.45) | SNCAMMP1MMP2MMP9MEN1 | |
| SCHEMBL6138727 | 0.89 | MAPT (0.45) | SNCAMMP1MMP2MMP9MEN1 | |
| SCHEMBL6139157 | 0.88 | MAPT (0.44) | SNCAMEN1MAPTKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6139024 | 0.88 | MAPT (0.44) | SNCAMMP1MMP2MMP9MEN1 | |
| Hydrochloric Acid SCHEMBL6139022 | 0.88 | MAPT (0.44) | SNCAMMP1MMP2MMP9MEN1 | |
| SCHEMBL6093397 | 0.85 | SNCA (0.70) | SNCAMMP1MMP2MMP9MAPT | |
| SCHEMBL6093403 | 0.85 | SNCA (0.70) | SNCAMMP1MMP2MMP9MAPT | |
| SCHEMBL6096716 | 0.82 | SNCA (0.67) | SNCAMMP1MMP2MMP9MAPT | |
| SCHEMBL6096714 | 0.82 | SNCA (0.67) | SNCAMMP1MMP2MMP9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7070626-B2 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-04 | — | — | US | disclosed |
| EP-1286953-B1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | KRT18, ALDH7A1, IK | SNCA 2855/4885MMP1 1394/4885MMP2 1401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.