Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 16/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6098215 | 0.92 | F10 (0.48) | F10GRM2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6097874 | 0.85 | F10 (0.52) | F10GRM2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6097877 | 0.84 | F10 (0.46) | F10GRM2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5389534 | 0.80 | MAOB (0.51) | F10 | |
| SCHEMBL6097345 | 0.79 | F10 (0.55) | F10GRM2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5392340 | 0.78 | F10 (0.45) | F10 | |
| SCHEMBL14580216 | 0.77 | F10 (0.58) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5384304 | 0.76 | F10 (0.57) | F10GRM2 | |
| SCHEMBL14580185 | 0.76 | F10 (0.56) | F10GRM2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14580181 | 0.75 | F10 (0.61) | F10CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030148-B2 | Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2006-04-18 | — | — | US | claimed |
| US-7030148-B2 | Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2006-04-18 | — | — | US | disclosed |