Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 5/20 | 0.70 |
| ▸ | KDM1A | O60341 | 3/20 | 0.60 |
| ▸ | MMP1 | P03956 | 7/20 | 0.51 |
| ▸ | MMP2 | P08253 | 7/20 | 0.51 |
| ▸ | MMP9 | P14780 | 7/20 | 0.51 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6096370 | 1.00 | SNCA (0.70) | SNCAKDM1AMMP1MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL6095713 | 0.98 | SNCA (0.68) | SNCAKDM1AMMP1MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL6095717 | 0.98 | SNCA (0.68) | SNCAKDM1AMMP1MMP2MMP9 | |
| SCHEMBL6094952 | 0.94 | SNCA (0.76) | SNCAKDM1AMMP1MMP2MMP9 | |
| SCHEMBL6094950 | 0.94 | SNCA (0.76) | SNCAKDM1AMMP1MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL7069532 | 0.93 | SNCA (0.74) | SNCAKDM1AMMP1MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL6573524 | 0.93 | SNCA (0.74) | SNCAKDM1AMMP1MMP2MMP9 | |
| SCHEMBL6097012 | 0.87 | KDM1A (0.65) | SNCAKDM1AMMP1MMP2MMP9 | |
| SCHEMBL6097007 | 0.87 | KDM1A (0.65) | SNCAKDM1AMMP1MMP2MMP9 | |
| SCHEMBL6096207 | 0.86 | SNCA (0.57) | SNCAKDM1AMMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7070626-B2 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-04 | — | — | US | claimed |
| EP-1286953-B1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-02-18 | — | — | EP | claimed |
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-16 | — | — | US | claimed |
| US-7070626-B2 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-04 | — | — | US | disclosed |
| EP-1286953-B1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-16 | — | — | US | disclosed |
| EP-1286953-A1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2002079144-A1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | KRT18, ALDH7A1, IK | SNCA 2855/4885KDM1A 2076/4885MMP1 1394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.