Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043127 | 0.90 | EGFR (0.88) | EGFRERBB2 | |
| SCHEMBL1730083 | 0.88 | EGFR (0.88) | EGFRERBB2 | |
| SCHEMBL4047226 | 0.84 | ERBB2 (0.85) | EGFRERBB2 | |
| SCHEMBL27561492 | 0.83 | EGFR (0.83) | EGFRERBB2 | |
| SCHEMBL1462065 | 0.82 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL1730679 | 0.82 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL4049084 | 0.81 | EGFR (0.90) | EGFRERBB2 | |
| SCHEMBL27871859 | 0.81 | EGFR (0.83) | EGFRERBB2 | |
| SCHEMBL15712478 | 0.81 | ERBB2 (0.58) | EGFRERBB2 | |
| SCHEMBL27888132 | 0.81 | EGFR (0.86) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112675-B2 | Pyrrolotriazine inhibitors of kinases | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-09-26 | — | — | US | disclosed |