SCHEMBL6100

SCHEMBL6100

CNC(=O)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 3/20 0.62
HDAC6 Q9UBN7 3/20 0.62
HDAC2 Q92769 2/20 0.62
HDAC3 O15379 1/20 0.61
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
IDO1 P14902 1/20 0.61
ALOX15 P16050 1/20 0.61
HDAC1 Q13547 1/20 0.61
CA9 Q16790 1/20 0.61
HDAC7 Q8WUI4 1/20 0.61
HSD17B10 Q99714 1/20 0.61
NCOR2 Q9Y618 1/20 0.61
TSHR P16473 2/20 0.58
HPGD P15428 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
HTT P42858 1/20 0.58
GAA P10253 1/20 0.56
PLK1 P53350 3/20 0.56
ALDH1A1 P00352 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11338414 0.97 HDAC8 (0.60) HDAC8HDAC6HDAC2HDAC3CA12
Methane SCHEMBL15893673 0.97 HDAC8 (0.67) HDAC8HDAC6HDAC2HDAC3CA12
SCHEMBL29273718 0.97 HDAC8 (0.60) HDAC8HDAC6HDAC2HDAC3CA12
Hydrochloric Acid SCHEMBL5866386 0.97 HDAC8 (0.60) HDAC8HDAC6HDAC2HDAC3CA12
SCHEMBL11130438 0.97 HDAC8 (0.60) HDAC8HDAC6HDAC2HDAC3CA12
SCHEMBL7796539 0.97 HDAC8 (0.60) HDAC8HDAC6HDAC2HDAC3CA12
Hydrochloric Acid SCHEMBL2915137 0.97 HDAC8 (0.60) HDAC8HDAC6HDAC2HDAC3CA12
Dimethylamine SCHEMBL10918737 0.97 HDAC8 (0.60) HDAC8HDAC6HDAC2HDAC3CA12
Hydrochloric Acid SCHEMBL5075431 0.97 HDAC8 (0.60) HDAC8HDAC6HDAC2HDAC3CA12
SCHEMBL8019806 0.97 HDAC8 (0.60) HDAC8HDAC6HDAC2HDAC3CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9622 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036715-A 2, 4-Diarylaminopyrimidine derivative containing benzodithioryl, and pharmaceutical composition and application thereof 盐城工业职业技术学院 2026-05-15 CN claimed
CN-122032648-A Liquid phase catalyst for hydrochlorination of acetylene and application thereof 天津大学 2026-05-15 CN claimed
EP-4709714-A1 SUBSTITUTED QUINOXALINES Mirati Therapeutics, Inc. (US) 2026-03-18 EP claimed
US-20260070879-A1 ISOXAZOLINE DERIVATIVES ELANCO TIERGESUNDHEIT AG (CH) 2026-03-12 US claimed
US-12565549-B2 Process to prepare a procatalyst for polymerization of olefins SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2026-03-03 US claimed
EP-4696832-A1 COLOURING COMPOSITION FOR THE PRINTING AND/OR DYEING OF TEXTILES, METHOD FOR THE PRINTING AND/OR DYEING OF TEXTILES, AND PRINTED SUBSTRATE EcoFusions GmbH i.Gr. (DE) 2026-02-18 EP claimed
US-12492193-B2 Pyrazole derivatives for the treatment of cystic fibrosis FONDAZIONE INSTITUTO ITALIANO DI TECNOLOGIA (IT) 2025-12-09 US claimed
US-12486260-B2 Indazolyl-isoxazole derivatives for the treatment of diseases such as cancer MERCK PATENT GMBH (DE) 2025-12-02 US claimed
US-12478594-B2 Methods of treatment of kidney injury associated with infection or trauma University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2025-11-25 US claimed
EP-4263533-B1 ERAP INHIBITORS UNIV LILLE (FR) 2025-08-20 EP claimed
EP-0039903-A2 8-Substituted pyrrolizidines and quaternary ammonium salts thereof SUNTORY KABUSHIKI KAISHA (JP) 1981-11-18 EP claimed
US-4293551-A N-Amino-3,4,5-trihydroxypiperidines, their production and their medicinal use BAYER AKTIENGESELLSCHAFT (DE) 1981-10-06 US claimed
US-4271303-A ISOINDOLE DYES FOR POLYESTERS BASF AKTIENGESELLSCHAFT (DE) 1981-06-02 US claimed
EP-0008058-A1 N-Amino-3,4,5-trihydroxypiperidines, methods for their preparation, medicaments containing them, method for the production of the medicaments and animal feedstuff containing said compounds BAYER AG (DE) 1980-02-20 EP claimed
US-RE30149-E OXIDATION OF 4-AMINOMETHYL-CYCLOHEXANE METHANOL AB KABI (SE) 1979-11-13 US claimed
US-4153608-A Anthraquinone vat dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1979-05-08 US claimed
US-4152356-A SELECTIVE CARBONYLATION OF 9,10-DIHYDROANTHRACENE TO FORM 9-FORMYL-9,10-DIHYDROANTHRACENE EXXON RESEARCH & ENGINEERING CO. (US) 1979-05-01 US claimed
US-4072463-A MONOAZO AND DISAZO DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DT) 1978-02-07 US claimed
US-4051168-A TO FORM FLUOROALKYL AROMATIC COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-27 US claimed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US claimed