Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6099130 | 1.00 | TACR1 (0.79) | TACR1 | |
| SCHEMBL6100129 | 0.92 | TACR1 (0.81) | TACR1 | |
| SCHEMBL6101280 | 0.92 | TACR1 (0.82) | TACR1 | |
| SCHEMBL6098193 | 0.89 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6098196 | 0.89 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6098093 | 0.88 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6098092 | 0.88 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6099023 | 0.87 | TACR1 (0.85) | TACR1 | |
| SCHEMBL6097474 | 0.86 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6097478 | 0.86 | TACR1 (1.00) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094779-B2 | Piperazine oxime dervatives having NK-1 receptor antagonistic activity | SOLVAY PHARMACEUTICALS B.V. (NL) | 2006-08-22 | — | — | US | disclosed |
| EP-1406894-B1 | PIPERAZINE OXIME DERIVATIVES HAVING NK-1 RECEPTOR ANTAGONISTIC ACTIVITY | SOLVAY PHARM BV (NL) | 2004-12-22 | — | — | EP | disclosed |