Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27479149 | 0.74 | HPGD (1.00) | HPGDALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL7132525 | 0.74 | HPGD (1.00) | HPGDALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL3454812 | 0.74 | HPGD (0.96) | HPGDALDH1A1MAPK1TSHRNPC1 | |
| SCHEMBL3456729 | 0.74 | HPGD (0.96) | HPGDALDH1A1MAPK1TSHRNPC1 | |
| SCHEMBL17626280 | 0.73 | DHODH (0.40) | HPGDALDH1A1MAPK1TSHRNPC1 | |
| SCHEMBL10721733 | 0.73 | HPGD (0.95) | HPGDALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL6614562 | 0.72 | HPGD (1.00) | HPGDALDH1A1MAPK1TSHRNPC1 | |
| SCHEMBL27978775 | 0.70 | HPGD (0.73) | HPGDALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL20197 | 0.70 | HPGD (0.73) | HPGDALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL1927946 | 0.69 | HPGD (1.00) | HPGDALDH1A1MAPK1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006048331-A1 | 11β-HSD1 INHIBITORS | EVOTEC AG (DE) | 2006-05-11 | — | — | WO | disclosed |