Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6102025 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAHTTKMT2ASTAT3 | |
| SCHEMBL6101614 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTKMT2ASTAT3 | |
| SCHEMBL6099042 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAHTTKMT2ASTAT3 | |
| SCHEMBL6097832 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTKMT2ASTAT3 | |
| SCHEMBL25289418 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTKMT2ASTAT3 | |
| SCHEMBL29430221 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTKMT2ASTAT3 | |
| SCHEMBL25292453 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTKMT2ASTAT3 | |
| SCHEMBL6100917 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTKMT2ASTAT3 | |
| SCHEMBL25289419 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTKMT2ASTAT3 | |
| SCHEMBL29430224 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTKMT2ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084176-B2 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2006-08-01 | — | — | US | claimed |
| US-20040248983-A1 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2004-12-09 | — | — | US | claimed |
| CN-1529692-A | N-arylphenylacetamide derivatives and medicinal compositions containing same | 大日本制药株式会社 | 2004-09-15 | — | — | CN | claimed |
| EP-1403235-A1 | N-ARYLPHENYLACETAMIDE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 2004-03-31 | — | — | EP | claimed |
| CN-1282640-C | N-arylphenylacetamide derivatives and medicinal compositions containing same | DAINIPPON PHARMACEUTICAL CO (JP) | 2006-11-01 | — | — | CN | disclosed |
| US-7084176-B2 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2006-08-01 | — | — | US | disclosed |
| US-20040248983-A1 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| CN-1529692-A | N-arylphenylacetamide derivatives and medicinal compositions containing same | 大日本制药株式会社 | 2004-09-15 | — | — | CN | disclosed |
| EP-1403235-A1 | N-ARYLPHENYLACETAMIDE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248983-A1 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | HRH2, CCR8, CYP2C8 | SMN1; SMN2 2474/4885LMNA 3086/4885HTT 1276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.