Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPPL2A | Q8TCT8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6101755 | 0.99 | SPPL2A (0.44) | SPPL2ACYP3A4MLNRABCB11LMNA | |
| SCHEMBL4975290 | 0.89 | SPPL2A (0.49) | SPPL2ACYP3A4MLNRABCB11LMNA | |
| SCHEMBL6101693 | 0.87 | MLNR (0.47) | SPPL2ACYP3A4MLNRABCB11LMNA | |
| SCHEMBL5026529 | 0.85 | SPPL2A (0.60) | SPPL2ACYP3A4MLNRABCB11LMNA | |
| SCHEMBL14189508 | 0.85 | SPPL2A (0.51) | SPPL2ACYP3A4MLNRABCB11LMNA | |
| Bromide SCHEMBL4972235 | 0.84 | SPPL2A (0.50) | SPPL2ACYP3A4MLNRABCB11LMNA | |
| SCHEMBL7518698 | 0.84 | SPPL2A (0.46) | SPPL2ACYP3A4MLNRABCB11LMNA | |
| SCHEMBL5914806 | 0.84 | SPPL2A (0.46) | SPPL2ACYP3A4MLNRABCB11LMNA | |
| SCHEMBL12434835 | 0.84 | SPPL2A (0.53) | SPPL2ACYP3A4MLNRABCB11LMNA | |
| SCHEMBL8238981 | 0.84 | SPPL2A (0.53) | SPPL2ACYP3A4MLNRABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7098202-B2 | Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 2006-08-29 | — | — | US | disclosed |