Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.80 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183787 | 0.89 | TP53 (1.00) | TP53TSHRALDH1A1GLACYP3A4 | |
| SCHEMBL3837348 | 0.80 | POLB (0.78) | TP53TSHRPOLBSMN1; SMN2SLC6A2 | |
| SCHEMBL3486247 | 0.79 | TP53 (0.71) | TP53TSHRALDH1A1GLACYP3A4 | |
| SCHEMBL4482255 | 0.79 | SLC6A2 (0.53) | TP53TSHRALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL4065279 | 0.78 | TP53 (0.69) | TP53TSHRALDH1A1GLASMN1; SMN2 | |
| SCHEMBL3454955 | 0.76 | TP53 (0.67) | TP53TSHRALDH1A1GLASMN1; SMN2 | |
| SCHEMBL4560227 | 0.75 | TP53 (0.65) | TP53TSHRALDH1A1GLASMN1; SMN2 | |
| SCHEMBL7845681 | 0.74 | TP53 (0.59) | TP53TSHRALDH1A1GLACYP3A4 | |
| SCHEMBL5517147 | 0.74 | TSHR (0.71) | TP53TSHRALDH1A1GLASMN1; SMN2 | |
| SCHEMBL1006444 | 0.73 | HTT (0.71) | TP53TSHRALDH1A1GLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6995269-B2 | Guanidinobenzamides | CHIRON CORPORATION (US) | 2006-02-07 | — | — | US | disclosed |