Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.67 |
| ▸ | ERBB2 | P04626 | 11/20 | 0.63 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | ERBB4 | Q15303 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2252480 | 0.96 | EGFR (0.66) | EGFRERBB2LCKERBB4 | |
| SCHEMBL2249784 | 0.93 | EGFR (0.75) | EGFRERBB2LCKERBB4 | |
| SCHEMBL2250704 | 0.89 | EGFR (0.57) | EGFRERBB2LCK | |
| SCHEMBL2249394 | 0.89 | EGFR (0.73) | EGFRERBB2LCKERBB4 | |
| SCHEMBL6102692 | 0.89 | EGFR (0.57) | EGFRERBB2LCKERBB4 | |
| SCHEMBL2247127 | 0.88 | EGFR (0.69) | EGFRERBB2LCKERBB4 | |
| SCHEMBL2248785 | 0.88 | EGFR (0.72) | EGFRERBB2LCKERBB4 | |
| SCHEMBL6104551 | 0.88 | EGFR (0.56) | EGFRERBB2LCK | |
| SCHEMBL2255364 | 0.86 | EGFR (0.68) | EGFRERBB2LCK | |
| SCHEMBL2251599 | 0.85 | EGFR (0.67) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006071079-A1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | HANMI PHARM. CO., LTD. (KR) | 2006-07-06 | — | — | WO | disclosed |