Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 12/20 | 0.56 |
| ▸ | EGFR | P00533 | 18/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2249379 | 0.89 | EGFR (0.65) | ERBB2EGFRLCKKDR | |
| SCHEMBL6111779 | 0.86 | EGFR (0.66) | ERBB2EGFRLCK | |
| SCHEMBL2252480 | 0.85 | EGFR (0.66) | ERBB2EGFRLCK | |
| SCHEMBL2250704 | 0.83 | EGFR (0.57) | ERBB2EGFRLCKKDR | |
| SCHEMBL2250018 | 0.83 | EGFR (0.68) | ERBB2EGFRLCKKDR | |
| SCHEMBL2249394 | 0.82 | EGFR (0.73) | ERBB2EGFRLCKKDR | |
| SCHEMBL6104551 | 0.82 | EGFR (0.56) | ERBB2EGFRLCK | |
| SCHEMBL2251599 | 0.82 | EGFR (0.67) | ERBB2EGFRKDR | |
| SCHEMBL23406741 | 0.81 | EGFR (0.59) | ERBB2EGFRLCKEPHA2KDR | |
| SCHEMBL21835302 | 0.81 | EGFR (0.59) | ERBB2EGFRLCKEPHA2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006071079-A1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | HANMI PHARM. CO., LTD. (KR) | 2006-07-06 | — | — | WO | disclosed |