Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 11/20 | 0.40 |
| ▸ | KDR | P35968 | 11/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.40 |
| ▸ | LCK | P06239 | 3/20 | 0.40 |
| ▸ | FYN | P06241 | 3/20 | 0.40 |
| ▸ | YES1 | P07947 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 7/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6103812 | 1.00 | PDGFRB (0.40) | PDGFRBKDRFGFR1LCKFYN | |
| SCHEMBL6103470 | 0.95 | KCNJ1 (0.39) | PDGFRBKDRFGFR1LCKFYN | |
| SCHEMBL6103466 | 0.95 | KCNJ1 (0.39) | PDGFRBKDRFGFR1LCKFYN | |
| SCHEMBL4304328 | 0.91 | PDGFRB (0.40) | PDGFRBKDRKITLRRK2 | |
| SCHEMBL4304329 | 0.91 | PDGFRB (0.40) | PDGFRBKDRKITLRRK2 | |
| SCHEMBL6104928 | 0.90 | PDGFRB (0.39) | PDGFRBKDRFGFR1KITHTR1A | |
| SCHEMBL6104933 | 0.90 | PDGFRB (0.39) | PDGFRBKDRFGFR1KITHTR1A | |
| SCHEMBL6103094 | 0.90 | PDGFRB (0.47) | PDGFRBKDRFGFR1LCKFYN | |
| SCHEMBL6103091 | 0.90 | PDGFRB (0.47) | PDGFRBKDRFGFR1LCKFYN | |
| SCHEMBL6102322 | 0.85 | PDGFRB (0.40) | PDGFRBKDRFGFR1LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004084-A1 | (3Z)-3-(2,3-dihydro-1H-inden-1-ylidene)-1,3-dihydro-2H-indol-2-ones as kinase inhibitors | ALLERGAN, INC. | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004084-A1 | (3Z)-3-(2,3-dihydro-1H-inden-1-ylidene)-1,3-dihydro-2H-indol-2-ones as kinase inhibitors | CDK2, ERBB2, MAP3K3 | PDGFRB 502/4885KDR 320/4885FGFR1 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.