Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6105994 | 0.89 | DPP4 (0.50) | DPP4ALDH1A1GAAHPGDCASP1 | |
| SCHEMBL6107959 | 0.86 | DPP4 (0.57) | DPP4 | |
| SCHEMBL6107578 | 0.86 | DPP4 (0.51) | DPP4ALDH1A1GAAHPGDCASP1 | |
| Hydrochloric Acid SCHEMBL5234017 | 0.84 | DPP4 (0.72) | DPP4 | |
| SCHEMBL6110160 | 0.84 | DPP4 (0.40) | DPP4ALDH1A1GAAHPGDCASP1 | |
| SCHEMBL6108589 | 0.83 | DPP4 (0.72) | DPP4 | |
| SCHEMBL6107250 | 0.83 | DPP4 (0.45) | DPP4 | |
| SCHEMBL5238230 | 0.82 | DPP4 (0.58) | DPP4ALDH1A1GAAHPGDCASP1 | |
| SCHEMBL5238238 | 0.81 | DPP4 (0.54) | DPP4ALDH1A1GAAHPGDCASP1 | |
| SCHEMBL6107650 | 0.80 | DPP4 (0.62) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034039-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |