Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.79 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.54 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61095 | 1.00 | PDPK1 (0.79) | PDPK1HTTLMNAALDH1A1TAS1R3 | |
| SCHEMBL29453898 | 1.00 | PDPK1 (0.79) | PDPK1HTTLMNAALDH1A1TAS1R3 | |
| SCHEMBL30142522 | 1.00 | PDPK1 (0.79) | PDPK1HTTLMNAALDH1A1TAS1R3 | |
| SCHEMBL61380 | 1.00 | PDPK1 (0.79) | PDPK1HTTLMNAALDH1A1TAS1R3 | |
| Hydrochloric Acid SCHEMBL31126266 | 0.98 | PDPK1 (0.76) | PDPK1HTTLMNAALDH1A1TAS1R3 | |
| Hydrochloric Acid SCHEMBL5795775 | 0.98 | PDPK1 (0.76) | PDPK1HTTLMNAALDH1A1TAS1R3 | |
| SCHEMBL2465738 | 0.88 | PDPK1 (1.00) | PDPK1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL61508 | 0.88 | PDPK1 (1.00) | PDPK1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL14612385 | 0.88 | PDPK1 (1.00) | PDPK1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL61509 | 0.88 | PDPK1 (1.00) | PDPK1ADRA2AADRA2BADRA2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013124250-A2 | FUNGICIDAL SUBSTITUTED THIOPHENES | BASF SE (DE) | 2013-08-29 | — | — | WO | claimed |
| WO-2024145483-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND METHODS OF MAKING AND USING THE SAME | HTG MOLECULAR DIAGNOSTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| US-11111270-B2 | Inhibitor of apoptosis protein (IAP) antagonists | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-09-07 | — | — | US | disclosed |
| US-10864217-B2 | Use of inhibitor of apoptosis protein (IAP) antagonists in HIV therapy | Sanford Burnham Prebys Medical Discovery Institute (US) | 2020-12-15 | — | — | US | disclosed |
| US-20200317731-A1 | Inhibitor of Apoptosis Protein (IAP) Antagonists | Sanford Burnham Prebys Medical Discovery Institute | 2020-10-08 | — | — | US | disclosed |
| US-20200121693-A1 | Use of Inhibitor of Apoptosis Protein (IAP) Antagonists in HIV Therapy | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | 2020-04-23 | — | — | US | disclosed |
| US-10544188-B2 | Inhibitor of apoptosis protein (IAP) antagonists | Sanford Burnham Prebys Medical Discovery Institute (US) | 2020-01-28 | — | — | US | disclosed |
| US-10358426-B2 | Fungicidal substituted 2-[2-halogenalkyl-4-(phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds | BASF Agro B.V. (NL) | 2019-07-23 | — | — | US | disclosed |
| US-20190135861-A1 | Inhibitor of Apoptosis Protein (IAP) Antagonists | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | 2019-05-09 | — | — | US | disclosed |
| US-20180044343-A1 | BICYCLIC IMIDAZOLO DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2018-02-15 | — | — | US | disclosed |
| US-20070249665-A1 | 1-aryl-4-substituted isoquinolines | NEUROGEN CORPORATION (US) | 2007-10-25 | — | — | US | disclosed |
| US-20070197522-A1 | Dpp-iv inhibitors | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2007-08-23 | — | — | US | disclosed |
| EP-1745024-A1 | 1-ARYL-4-SUBSTITUTED ISOQUINOLINES | NEUROGEN CORPORATION (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005110991-A1 | 1-ARYL-4-SUBSTITUTED ISOQUINOLINES | NEUROGEN CORPORATION (US) | 2005-11-24 | — | — | WO | disclosed |
| EP-1565452-A2 | 3-SUBSTITUTED-6-ARYL PYRIDINES AS LIGANDS OF C5A RECEPTORS | NEUROGEN CORPORATION (US) | 2005-08-24 | — | — | EP | disclosed |
| US-20040158067-A1 | 3-substituted-6-aryl pyridines | NEUROGEN CORPORATION | 2004-08-12 | — | — | US | disclosed |
| WO-2004043925-A2 | 3-SUBSTITUTED-6-ARYL PYRIDINED AS LIGANDS OF C5A RECEPTORS | NEUROGEN CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
| EP-0595851-B1 | PROCESS FOR PREPARING SERTRALINE INTERMEDIATES | PFIZER LTD (GB) | 1996-01-10 | — | — | EP | disclosed |
| US-5442116-A | Process for preparing sertraline intermediates | PFIZER INC. (US) | 1995-08-15 | — | — | US | disclosed |
| WO-1993001161-A1 | PROCESS FOR PREPARING SERTRALINE INTERMEDIATES | PFIZER LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10864217-B2 | Use of inhibitor of apoptosis protein (IAP) antagonists in HIV therapy | API5, BIRC3, BIRC5 | PDPK1 1388/4885HTT 3354/4885LMNA 2103/4885 |
| US-20180044343-A1 | BICYCLIC IMIDAZOLO DERIVATIVE | PDE3A, PDE2A, PDE5A | PDPK1 110/4885HTT 4781/4885LMNA 2416/4885 |
| US-20200317731-A1 | Inhibitor of Apoptosis Protein (IAP) Antagonists | API5, XIAP, BIRC5 | PDPK1 1004/4885HTT 2134/4885LMNA 558/4885 |
| US-20070249665-A1 | 1-aryl-4-substituted isoquinolines | C3AR1, C5AR1, C5AR2 | PDPK1 2951/4885HTT 3970/4885LMNA 3893/4885 |
| US-20070197522-A1 | Dpp-iv inhibitors | DPP7, DPP4, DPP3 | PDPK1 1652/4885HTT 3749/4885LMNA 3964/4885 |
| US-10358426-B2 | Fungicidal substituted 2-[2-halogenalkyl-4-(phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds | CYP2E1, TH, CYP1A1 | PDPK1 1028/4885HTT 2864/4885LMNA 4335/4885 |
| US-10544188-B2 | Inhibitor of apoptosis protein (IAP) antagonists | API5, XIAP, BIRC5 | PDPK1 1004/4885HTT 2134/4885LMNA 558/4885 |
| US-11111270-B2 | Inhibitor of apoptosis protein (IAP) antagonists | API5, XIAP, BIRC5 | PDPK1 1004/4885HTT 2134/4885LMNA 558/4885 |
| US-20200121693-A1 | Use of Inhibitor of Apoptosis Protein (IAP) Antagonists in HIV Therapy | API5, BIRC3, BIRC5 | PDPK1 1388/4885HTT 3354/4885LMNA 2103/4885 |
| US-20190135861-A1 | Inhibitor of Apoptosis Protein (IAP) Antagonists | API5, XIAP, BIRC5 | PDPK1 1004/4885HTT 2134/4885LMNA 558/4885 |
| US-20040158067-A1 | 3-substituted-6-aryl pyridines | C3AR1, C5AR1, C5AR2 | PDPK1 2612/4885HTT 4549/4885LMNA 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.