SCHEMBL6109482

SCHEMBL6109482

CC(C)Cn1c(CN(C(=O)O)C(C)(C)C)c(-c2ccc(Cl)cc2)c2cc(OCc3ccccc3)ccc2c1=O

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6110225 0.94 DPP4 (0.57) DPP4
SCHEMBL6106801 0.93 DPP4 (0.56) DPP4
SCHEMBL6108722 0.92 DPP4 (0.51) DPP4
SCHEMBL6107683 0.91 DPP4 (0.58) DPP4
SCHEMBL6106955 0.88 DPP4 (0.63) DPP4
SCHEMBL6109828 0.88 DPP4 (0.50) DPP4
SCHEMBL5236698 0.86 DPP4 (0.57) DPP4
SCHEMBL6107884 0.86 DPP4 (0.56) DPP4
SCHEMBL6109132 0.86 DPP4 (0.46) DPP4
SCHEMBL6108716 0.85 DPP4 (0.47) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7034039-B2 Fused heterocyclic compounds TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-04-25 US disclosed