Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6109750 | 0.91 | DPP4 (0.46) | DPP4 | |
| SCHEMBL6107920 | 0.89 | DPP4 (0.54) | DPP4 | |
| SCHEMBL6109503 | 0.88 | DPP4 (0.53) | DPP4 | |
| SCHEMBL6109828 | 0.88 | DPP4 (0.50) | DPP4KCNA5KCNH2 | |
| SCHEMBL6108232 | 0.88 | DPP4 (0.62) | DPP4KCNA5KCNH2 | |
| SCHEMBL6108716 | 0.87 | DPP4 (0.47) | DPP4 | |
| SCHEMBL6109442 | 0.87 | DPP4 (0.56) | DPP4 | |
| SCHEMBL6108638 | 0.86 | DPP4 (0.45) | DPP4 | |
| SCHEMBL6700296 | 0.85 | DPP4 (0.47) | DPP4KCNA5KCNH2 | |
| SCHEMBL5236927 | 0.85 | KCNA5 (0.44) | DPP4KCNA5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034039-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |