Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.53 |
| ▸ | EGFR | P00533 | 12/20 | 0.52 |
| ▸ | IGF1R | P08069 | 8/20 | 0.52 |
| ▸ | ERBB4 | Q15303 | 7/20 | 0.52 |
| ▸ | ABL1 | P00519 | 6/20 | 0.52 |
| ▸ | SRC | P12931 | 5/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.52 |
| ▸ | LCK | P06239 | 3/20 | 0.52 |
| ▸ | FLT3 | P36888 | 3/20 | 0.52 |
| ▸ | PLK4 | O00444 | 2/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 2/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.52 |
| ▸ | PAK4 | O96013 | 2/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.52 |
| ▸ | INSR | P06213 | 2/20 | 0.52 |
| ▸ | FYN | P06241 | 2/20 | 0.52 |
| ▸ | CDK1 | P06493 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110007 | 1.00 | KDR (0.53) | KDREGFRIGF1RERBB4ABL1 | |
| SCHEMBL6110001 | 1.00 | KDR (0.53) | KDREGFRIGF1RERBB4ABL1 | |
| SCHEMBL3832911 | 0.93 | EGFR (0.47) | KDREGFRIGF1RERBB4ABL1 | |
| SCHEMBL3832909 | 0.93 | EGFR (0.47) | KDREGFRIGF1RERBB4ABL1 | |
| SCHEMBL3832912 | 0.93 | EGFR (0.47) | KDREGFRIGF1RERBB4ABL1 | |
| SCHEMBL6108972 | 0.86 | EGFR (0.56) | KDREGFRIGF1RERBB4ABL1 | |
| SCHEMBL6108968 | 0.86 | EGFR (0.56) | KDREGFRIGF1RERBB4ABL1 | |
| SCHEMBL6108970 | 0.86 | EGFR (0.56) | KDREGFRIGF1RERBB4ABL1 | |
| SCHEMBL3812024 | 0.84 | KDR (0.55) | KDREGFRIGF1RERBB4ABL1 | |
| SCHEMBL3820304 | 0.79 | SRC (0.55) | KDREGFRIGF1RERBB4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025383-A1 | Aminobenzoxazoles as therapeutic agents | ABBOTT LABORATORIES | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025383-A1 | Aminobenzoxazoles as therapeutic agents | ABL1, MAP3K19, MAP3K20 | KDR 2441/4885EGFR 506/4885IGF1R 2859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.